DISEASES >> HIV and AIDS
Human Immunodeficiency Virus (
HIV) infections may be caused by
one of two retroviruses,
HIV-1 or
HIV-2.
HIV-1
has caused a worldwide epidemic, but
HIV-2 tends to be limited
to West Africa.
HIV progressively destroys some types of white blood cells called
CD4+ lymphocytes. Lymphocytes help defend the body against foreign cells, infectious
organisms and cancer. Thus, when
HIV destroys CD4+ lymphocytes,
people become susceptible to attack by other infectious organisms. Many of the complications
of
HIV infection, including death, usually result from these other
infections and not from
HIV infection directly.
Acquired immunodeficiency syndrome (
AIDS) is the most severe form
of
HIV infection.
HIV infection is considered
to be
AIDS when at least one serious complicating illness develops
or the number (count) of CD4+ lymphocytes decreases substantially.
HIV is spread primarily by exchange of bodily fluids like blood, semen and blood
products.
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